
amivudine, A Nucleoside Analogue, Is Phosphorylated In The Body To The Active Triphosphate Form. In The Active Form, It Inhibits Hepatitis B Virus Polymerase And HIV Reverse Transcriptase Enzymes. Absorption: Rapidly Absorbed From The GI Tract, Delayed If Taken With Food (Oral); Peak Plasma Concentrations After 1 Hr. Distribution: Crosses The Blood-Brain Barrier And Placenta; Enters Breast Milk. Protein-Binding: Up To 36%. Metabolism: Intracellular; Low Hepatic Metabolism. Excretion: Via Urine (As Unchanged Drug); 5-7 Hr (Elimination Half-Life).
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MEDIFLORA PHARMASI
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